Microsoft 365 Security Best Practices: How to Protect Your Business Data Effectively
With more than 3 million organizations worldwide using Microsoft 365, the platform now represents nearly 30% of the global productivity software market. Microsoft 365 powers daily business operations—from email and collaboration to file storage and project management—making it a mission-critical environment for most organizations.
However, widespread adoption also makes Microsoft 365 a prime target for cyberattacks. Ensuring proper security, resilience, and compliance is no longer optional. This is where a well-defined security strategy—and the expertise of RoundAssist—becomes essential.
Why Microsoft 365 Security Should Be a Priority
Microsoft 365 supports a wide range of business-critical tools, including:
- Microsoft Teams for collaboration and communication
- Outlook for enterprise email
- OneDrive for file storage
- SharePoint for document and project management
Because these tools directly impact productivity and collaboration, any data loss, breach, or outage can disrupt business operations immediately. At the same time, regulatory compliance requirements demand strict control over how data is stored, accessed, and protected.
Despite Microsoft’s strong infrastructure, security gaps often arise at the configuration, access, and data protection levels—areas that remain the customer’s responsibility.
Understanding the Risks to Your Microsoft 365 Data
Microsoft 365 environments face a wide range of threats. A well-known example occurred in 2020, when 250 million Microsoft customer records were accidentally exposed due to misconfigured data storage—highlighting how even major platforms are vulnerable when security controls fail.
Common risks include:
- Accidental or intentional data deletion
- Unauthorized access and account takeover
- Ransomware and malware attacks
- Platform outages
- Phishing and credential theft
- Limited native recovery options
- Regulatory compliance violations
Without proactive security controls, these risks can quickly escalate into business-critical incidents.
Microsoft’s Shared Responsibility Model Explained
Microsoft operates under a shared responsibility model. While Microsoft secures the underlying cloud infrastructure, customers are fully responsible for their data within Microsoft 365.
This means your organization is accountable for:
- Data protection and retention
- Backup and recovery
- Access management
- Compliance with industry regulations
To strengthen your security posture, RoundAssist recommends focusing on access control, identity protection, comprehensive backups, monitoring, and regulatory compliance.
Are Native Microsoft 365 Security Features Enough?
Microsoft 365 includes baseline security features such as spam filtering, malware protection, and multi-factor authentication (MFA). While helpful, native capabilities leave significant gaps, particularly around backup, retention, and granular recovery.
Limitations of native Microsoft 365 backup include:
- Retention capped at one year for OneDrive, SharePoint, and Exchange
- Limited restore granularity (entire mailboxes, sites, or accounts)
- Minimal file-level recovery options
- Restore speeds and scalability constraints
- Insufficient protection against ransomware and insider threats
In real-world scenarios involving outages, ransomware, or accidental deletion, native tools alone are not enough.
Real-World Microsoft 365 Data Breaches
Attackers increasingly target Microsoft 365 using advanced techniques such as:
- Password spraying via large botnets
- Exploiting non-interactive sign-ins
- Phishing campaigns using fake OAuth apps
- MFA bypass and token theft
In several cases, attackers impersonated trusted brands like Adobe or DocuSign, tricking users into granting OAuth access and silently compromising accounts.
Mitigation requires:
- Enforcing admin consent for OAuth apps
- Monitoring OAuth permissions and sign-in logs
- Blocking legacy authentication
- Continuous user security awareness training
Microsoft 365 Security Best Practices
To secure your Microsoft 365 environment effectively, RoundAssist recommends a layered security approach that combines prevention, detection, and recovery.
Access Controls
- Implement Role-Based Access Control (RBAC)
- Apply the principle of least privilege
- Minimize the number of global admins
- Regularly review and revoke unnecessary permissions
Strong Authentication
- Enforce multi-factor authentication for all users
- Combine authentication methods where possible
- Monitor sign-in behavior and anomalies
Identity and User Management
- Centralize identity management using Azure Active Directory
- Enforce strong password policies
- Review user access regularly
Secure Single Sign-On (SSO)
- Use Azure AD as a trusted identity provider
- Apply conditional access policies
- Continuously review SSO configurations
Email and Collaboration Protection
- Enable Microsoft Defender for Office 365
- Use Exchange Online Protection (EOP)
- Implement Data Loss Prevention (DLP) policies
Network Security
- Protect networks with firewalls, VPNs, antivirus, and DDoS mitigation
- Integrate Microsoft Defender across endpoints
Third-Party Integrations
- Vet all third-party tools carefully
- Ensure compatibility with backup and compliance requirements
- Verify certifications such as SOC 2 Type II
Logging, Monitoring, and Audits
- Enable comprehensive audit logging
- Monitor user activity and configuration changes
- Conduct regular security audits and employee training
Metadata and DevSecOps Protection
- Secure metadata alongside primary data
- Ensure backups include configuration and system dependencies
- Conduct continuous security scans
Backup and Recovery: The Missing Layer in Microsoft 365 Security
Microsoft 365 does not provide full backup or disaster recovery. According to the shared responsibility model, you are required to implement your own backup strategy.
A robust Microsoft 365 backup solution—such as those deployed by RoundAssist—should include:
- Full coverage for Exchange, OneDrive, SharePoint, and Teams
- Automated and scheduled backups
- Unlimited retention for compliance and archiving
- Support for the 3-2-1 backup rule
- Ransomware-resistant storage
- Encryption in transit and at rest
- Granular, point-in-time, and cross-tenant restore options
- Compliance with ISO 27001 and SOC 2 Type II
A backup is only as good as its restore capabilities—and recovery speed can determine whether your business stays operational during an incident.
Final Thoughts: Secure Microsoft 365 the Right Way
Microsoft 365 simplifies collaboration and productivity—but security, compliance, and data resilience require expert configuration and ongoing management.
By combining best practices, advanced monitoring, and enterprise-grade backup and recovery, organizations can significantly reduce risk and ensure business continuity.
Secure Your Microsoft 365 Environment with RoundAssist
RoundAssist helps organizations design, implement, and manage secure Microsoft 365 environments—from access controls and monitoring to backup and disaster recovery.
Contact RoundAssist today to assess your Microsoft 365 security posture and protect your data before threats become incidents.


